FATE OF M1 CONVERTED M2 OOCYTE AND ITS DEVELOPMENT POTENTIAL

To evaluate the development potential of immature metaphase 1 oocytes when converted to mature M2 within 2 6 hours. A total 620 cycles from June 2019 Oct 2020 at IVF unit IKDRC hospital, ICSI was performed on 4,975 out which 398 were (M1) time denudation .Immature M1 evaluated every hours for maturation status and divided accordingly into three groups, in group (n=152) first 2hours, B (n= 98) 4 C (n=48) after hyaluronidase then ICSI’ed .Embryos cultured droplet culture individually fertilization check 17 ± post ovum pickup (Istanbul 2010), female aged >36 years, oocyte retrieved < or > 10 excluded study other inclusion exclusion criteria’s similar all groups. Primary outcomes rate, cleavage rate blastocyst formation rate. In Group where higher (60.5% vs 57.1% 56.1% ,p=0.001)than hours, significant difference observed ,cleavage is also significantly as compared (80.4%vs 60%vs 59.2%, p<0.001) respectively Blastocyst than (27.1% 12.5% vs11.1%,p<0.001). Oocytes that found have better those around However rates groups but A. It reflects fact patients having lower matured oocytes, these can be useful resource their reserve.